Porcine IL-27A(Interleukin-27 subunit alpha) ELISA Kit

Este producto es parte de IL27 - interleukin 27
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935106861
info@markelab.com
name
Porcine IL-27A(Interleukin-27 subunit alpha) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EP0302

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
porcine
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
15.625-1000pg/ml
Size 1
96T
Sample Type
Busacar en las instrucciones
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
Q5S1V9
Alias
p28,IL30,IL-27,IL27A,IL-27A,IL27p28,IL-27 subunit alpha,IL-27-A,Interleukin-30,p28
Background
Elisa Kits IL27
Status
RUO

Interleukin 27 (IL27) is a heterodimeric cytokine that belongs to the IL-12 cytokine family and plays a pivotal role in regulating immune responses. IL-27 is produced primarily by antigen-presenting cells (APCs), such as dendritic cells, macrophages, and monocytes, following activation by various pathogen-associated signals. Its primary function is to modulate T cell responses, particularly by promoting the differentiation of T helper 1 (Th1) cells while simultaneously limiting excessive inflammatory responses through immune suppression. This dual role positions IL-27 as a key regulator of both pro-inflammatory and anti-inflammatory immune responses. IL-27 is composed of two distinct subunits: EBI3 (Epstein-Barr virus-induced gene 3) and p28, which together form the functional cytokine. IL-27 signals through a heterodimeric receptor composed of IL-27R (WSX-1) and gp130, activating a range of signaling pathways that control immune function, including the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway.

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