Polycomb Complex Protein BMI-1 (BMI1) Peptide
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Description
Polycomb Complex Protein BMI-1 (BMI1) Peptide is a synthetic peptide. This peptide is used in the production of
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Polycomb Complex Protein BMI-1 (BMI1) |
| Host | Synthetic |
| Assay Type | Activity: Not tested. Sequence Fragment: Internal region, 237-251 AA: C-SHQRDGLTNAGELES |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 648, 12151 |
| NCBI Accession | NP_005171.4 |
| Background | Protein BMI1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water. |
Descripción
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Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
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