Poly ADP Ribose Polymerase 3 (PARP3) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
PARP3 Antibody is a Goat Polyclonal antibody against PARP3.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Poly ADP Ribose Polymerase 3 (PARP3) |
| Host | Goat |
| Reactivity | Human |
| Recommended Dilution | P-ELISA: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 10039 |
| NCBI Accession | NP_001003931.2, NP_001003935.2 |
| Background | Antibody anti-PARP3 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
Related Products
anti- PARP3 antibody
Involved in the base excision repair(BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
Ver Producto
Poly ADP Ribose Polymerase 3 (PARP3) Antibody
PARP3 Antibody is a Rabbit Polyclonal antibody against PARP3. The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Ver Producto
Poly ADP Ribose Polymerase 3 (PARP3) Antibody
Rabbit polyclonal antibody against PARP3 protein. Immunogen region is N-terminal.
Ver Producto