Platelet Glycoprotein Ib Alpha Chain (GP1BA) Antibody
364€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Platelet Glycoprotein Ib Alpha Chain (GP1BA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx231479
tested applications
ELISA, WB, IHC, IP
Description
CD42b Antibody is a Rabbit Polyclonal against CD42b.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Platelet Glycoprotein Ib Alpha Chain (GP1BA) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07359 |
| Alias | BSS,GP1B,VWDP,CD42B,GPIbA,BDPLT1,BDPLT3,DBPLT3,GPIbalpha,CD42b-alpha,Platelet glycoprotein Ib alpha chain,GP-Ib alpha,GPIb-alpha, Glycoprotein Ibalpha,CD42b-alpha |
| Background | Antibody anti-GP1BA |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Glycoprotein Ib platelet subunit alpha (GP1BA) is a critical component of the glycoprotein Ib-IX-V complex (GPIb-IX-V) on the surface of platelets. This complex plays a central role in the process of hemostasis, specifically in the adhesion of platelets to the damaged endothelium at sites of vascular injury. Hemostasis is crucial for preventing blood loss and initiating the wound healing process, and the proper functioning of the GPIb-IX-V complex is vital for platelet tethering under high shear stress conditions, such as in arterioles. GP1BA is the alpha subunit of GPIb, which is responsible for mediating the interaction with von Willebrand factor (vWF), a plasma glycoprotein that anchors platelets to the site of injury. Through its interactions with vWF, GP1BA enables the binding of platelets to exposed subendothelial matrix components, initiating platelet activation and aggregation.
Related Products
GP1BA antibody
Ver Producto
Recombinant Human GP1BA
Ver Producto
Platelet Glycoprotein Ib Alpha Chain (GP1BA) Antibody
Glycoprotein Ib (Platelet), Alpha Polypeptide Antibody is a Rabbit Polyclonal antibody against Glycoprotein Ib (Platelet), Alpha Polypeptide.
Ver Producto