Platelet Endothelial Cell Adhesion Molecule (PECAM1) Antibody (PE / Cyanine 5)
429€ (100 tests)
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Name
Platelet Endothelial Cell Adhesion Molecule (PECAM1) Antibody (PE / Cyanine 5)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx347034
Tested Applications
FCM
Description
Platelet Endothelial Cell Adhesion Molecule (PECAM1) Antibody (PE / Cyanine 5) is a Mouse against Platelet Endothelial Cell Adhesion Molecule (PECAM1).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Platelet Endothelial Cell Adhesion Molecule (PECAM1) Immunogen: Leukocytes of patient suffering from LGL-type leukaemia. |
| Host | Mouse |
| Reactivity | Human |
| Conjugation | PE / Cyanine 5 |
| Isotype | IgG1 |
| Clone ID | S860 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P16284 |
| Gene ID | 5175 |
| Alias | CD31,PECA1,PECAM-1,endoCAM,CD31/EndoCAM,Platelet endothelial cell adhesion molecule,GPIIA' |
| Background | Antibody anti-PECAM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
PECAM1 (Platelet and Endothelial Cell Adhesion Molecule 1), also known as CD31, is an integral member of the immunoglobulin (Ig) superfamily and functions primarily as a cell adhesion molecule. It plays critical roles in various physiological and pathological processes, including leukocyte transmigration, angiogenesis, vascular integrity, and immune response regulation. PECAM-1 is highly expressed on the surface of endothelial cells lining blood vessels, platelets, monocytes, neutrophils, and some subsets of T cells. Its pivotal role in mediating cell-cell interactions makes it central to maintaining vascular homeostasis and coordinating immune responses. PECAM-1 is widely recognized for its involvement in processes like leukocyte extravasation, where it facilitates the migration of immune cells across the endothelium during inflammation. Additionally, it serves as an essential player in maintaining the structural integrity of the vascular endothelium and modulating signaling pathways linked to cell survival and inflammation. Given its broad expression and functional diversity, PECAM-1 has been a focal point of research in vascular biology, inflammation, and cardiovascular diseases.
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