Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody (PerCP / Cyanine 5.5)

Este producto es parte de PECAM1 - platelet and endothelial cell adhesion molecule 1
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195€ (20 tests)

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935106861
info@markelab.com
name
Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody (PerCP / Cyanine 5.5)
category
Primary Antibodies
provider
Abbexa
reference
abx228490
tested applications
FCM

Description

CD31 Antibody (PerCP / Cyanine 5.5) is a Human Monoclonal Antibody against CD31.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetPlatelet And Endothelial Cell Adhesion Molecule 1 (CD31)
HostMouse
ReactivityHuman
ClonalityMonoclonal
ConjugationPerCP / Cyanine 5.5
IsotypeIgG1
Size 120 tests
Size 2100 tests
Size 3200 tests
Tested ApplicationsFCM
BufferPBS with 0.05% Proclin300, 1% BSA.
AvailabilityShipped within 5-15 working days.
StorageAliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze.
Dry IceNo
UniProt IDP16284
Gene ID5175
AliasCD31,PECA1,PECAM-1,endoCAM,CD31/EndoCAM,Platelet endothelial cell adhesion molecule,GPIIA'
BackgroundAntibody anti-PECAM1
StatusRUO

Descripción

PECAM1 (Platelet and Endothelial Cell Adhesion Molecule 1), also known as CD31, is an integral member of the immunoglobulin (Ig) superfamily and functions primarily as a cell adhesion molecule. It plays critical roles in various physiological and pathological processes, including leukocyte transmigration, angiogenesis, vascular integrity, and immune response regulation. PECAM-1 is highly expressed on the surface of endothelial cells lining blood vessels, platelets, monocytes, neutrophils, and some subsets of T cells. Its pivotal role in mediating cell-cell interactions makes it central to maintaining vascular homeostasis and coordinating immune responses. PECAM-1 is widely recognized for its involvement in processes like leukocyte extravasation, where it facilitates the migration of immune cells across the endothelium during inflammation. Additionally, it serves as an essential player in maintaining the structural integrity of the vascular endothelium and modulating signaling pathways linked to cell survival and inflammation. Given its broad expression and functional diversity, PECAM-1 has been a focal point of research in vascular biology, inflammation, and cardiovascular diseases.

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