Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody (AF647)
221€ (50 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody (AF647)
category
Primary Antibodies
provider
Abbexa
reference
abx229383
tested applications
FCM
Description
CD31 Antibody (AF647) is a Mouse Monoclonal Antibody against CD31.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | AF647 |
| Isotype | IgG2a Kappa |
| Size 1 | 50 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q08481 |
| Gene ID | 18613 |
| Alias | CD31,PECA1,PECAM-1,endoCAM,CD31/EndoCAM,Platelet endothelial cell adhesion molecule,GPIIA' |
| Background | Antibody anti-PECAM1 |
| Status | RUO |
Descripción
PECAM1 (Platelet and Endothelial Cell Adhesion Molecule 1), also known as CD31, is an integral member of the immunoglobulin (Ig) superfamily and functions primarily as a cell adhesion molecule. It plays critical roles in various physiological and pathological processes, including leukocyte transmigration, angiogenesis, vascular integrity, and immune response regulation. PECAM-1 is highly expressed on the surface of endothelial cells lining blood vessels, platelets, monocytes, neutrophils, and some subsets of T cells. Its pivotal role in mediating cell-cell interactions makes it central to maintaining vascular homeostasis and coordinating immune responses. PECAM-1 is widely recognized for its involvement in processes like leukocyte extravasation, where it facilitates the migration of immune cells across the endothelium during inflammation. Additionally, it serves as an essential player in maintaining the structural integrity of the vascular endothelium and modulating signaling pathways linked to cell survival and inflammation. Given its broad expression and functional diversity, PECAM-1 has been a focal point of research in vascular biology, inflammation, and cardiovascular diseases.
Related Products
Human PECAM-1(Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit
Ver Producto
Mouse PECAM-1/CD31(Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit
Ver Producto