Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody

Este producto es parte de PECAM1 - platelet and endothelial cell adhesion molecule 1
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559€ (2 ml)

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935106861
info@markelab.com
name
Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx413322
tested applications
IHC, FCM

Description

Platelet And Endothelial Cell Adhesion Molecule 1 (CD31) Antibody is a Mouse Monoclonal antibody against Platelet And Endothelial Cell Adhesion Molecule 1 (CD31).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Platelet And Endothelial Cell Adhesion Molecule 1 (CD31)
Host
Mouse
Reactivity
Pig
Recommended Dilution
Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgM
Purification
Unpurified supernatant
Size 1
2 ml
Form
Liquid
Tested Applications
IHC, FCM
Buffer
Contains sodium azide.
Availability
Shipped within 3-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q95242
Alias
CD31,PECA1,PECAM-1,endoCAM,CD31/EndoCAM,Platelet endothelial cell adhesion molecule,GPIIA'
Background
Antibody anti-PECAM1
Status
RUO

Descripción

PECAM1 (Platelet and Endothelial Cell Adhesion Molecule 1), also known as CD31, is an integral member of the immunoglobulin (Ig) superfamily and functions primarily as a cell adhesion molecule. It plays critical roles in various physiological and pathological processes, including leukocyte transmigration, angiogenesis, vascular integrity, and immune response regulation. PECAM-1 is highly expressed on the surface of endothelial cells lining blood vessels, platelets, monocytes, neutrophils, and some subsets of T cells. Its pivotal role in mediating cell-cell interactions makes it central to maintaining vascular homeostasis and coordinating immune responses. PECAM-1 is widely recognized for its involvement in processes like leukocyte extravasation, where it facilitates the migration of immune cells across the endothelium during inflammation. Additionally, it serves as an essential player in maintaining the structural integrity of the vascular endothelium and modulating signaling pathways linked to cell survival and inflammation. Given its broad expression and functional diversity, PECAM-1 has been a focal point of research in vascular biology, inflammation, and cardiovascular diseases.

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