Pig Transforming Growth Factor Beta 3 (TGFb3) Protein

Este producto es parte de TGFB- Transforming Growth Factor Beta
Pig Transforming Growth Factor Beta 3 (TGFb3) Protein

Pida mas información

935106861

info@markelab.com

Precio

377€ (50 µg)

Protein TGFB3

proveedor

Abbexa

reference

abx168801

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Pig TGFb3 Protein is a recombinant Pig protein produced in a Prokaryotic expression system (E. coli). This protein is the immunogen for the following antibody:


Background

TGFB3 is another member of the TGF-β family that is predominantly involved in embryonic development, tissue remodeling, and wound healing. TGFB3 regulates processes such as epithelial-mesenchymal transition (EMT), extracellular matrix (ECM) deposition, and immune suppression. It is highly expressed during palatogenesis, craniofacial development, and lung morphogenesis, where it plays an essential role in cell signaling and tissue architecture. TGFB3 facilitates proper scar formation and tissue repair by modulating fibroblast activation and ECM production while reducing excessive fibrosis. In cancer, TGFB3 contributes to tumor progression by inducing EMT and promoting metastatic dissemination. Mutations or dysregulation of TGFB3 are associated with cleft palate, cardiovascular abnormalities, and fibrotic diseases. Knockout models reveal impaired wound healing, disrupted tissue morphogenesis, and craniofacial defects, highlighting TGFB3’s role in tissue development, regeneration, and fibrotic regulation.

Características del producto

category

Proteins and Peptides


origin

Pig


host

E. coli


immunogen target

Transforming Growth Factor Beta 3 (TGFb3)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 16.4 kDa Observed MW: 16 kDa Concentration: Prior to lyophilization: 350 µg/ml Sequence Fragment: Ala298-Ser409 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TGFB3


dry ice

No


availability

Shipped within 5-7 working days.


alias

ARVD,ARVD1,LDS5,RNHF,TGF-beta3,Latency-associated peptide LAP,Transforming growth factor beta-3


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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