Pig TNF receptor-associated factor 6 (TRAF6) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Pig TNF receptor-associated factor 6 (TRAF6) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx520826
Tested Applications
ELISA
Description
Pig TNF receptor-associated factor 6 (TRAF6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig TNF receptor-associated factor 6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | TNF receptor-associated factor 6 (TRAF6) |
| Reactivity | Pig |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | A7XUJ6 |
| Alias | TRAF-6,TRAF6, MGC:3310, RNF85, TNF receptor associated factor 6 |
| Background | Elisa Kits for: TRAF6 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
TRAF6 is a multifunctional adaptor protein that regulates signaling downstream of TNFR superfamily members, Toll-like receptors (TLRs), and IL-1 receptors. It activates key pathways, including NF-κB, JNK, and Akt, to mediate inflammatory responses, innate immunity, and bone homeostasis. TRAF6 also functions as an E3 ubiquitin ligase, facilitating K63-linked ubiquitination of signaling intermediates like TAK1, IKK, and Akt to promote downstream activation. It plays essential roles in immune cell activation, osteoclast differentiation, and autophagy regulation. TRAF6 is widely expressed in immune cells, bone tissue, and epithelial cells, where it supports pathogen recognition, inflammatory signaling, and bone remodeling. Dysregulation of TRAF6 is associated with autoimmune diseases, chronic inflammation, osteoporosis, and cancer due to hyperactive NF-κB signaling and impaired bone resorption. Knockout models exhibit immune deficiencies, defective TLR signaling, impaired bone development, and increased susceptibility to infections, underscoring its critical role in immunity, inflammation, and skeletal homeostasis.
Productos relacionados
TNF Receptor-Associated Factor 6 (TRAF6) Antibody
TRAF6 Antibody is a Rabbit Polyclonal antibody against TRAF6. The protein encoded by this gene is a member of the TNF re…
Ver producto
TNF Receptor-Associated Factor 6 (TRAF6) Antibody
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins …
Ver producto
TNF Receptor-Associated Factor 6 (TRAF6) Antibody
Rabbit Polyclonal against the TRAF6 protein.…
Ver producto