Pig Mineralocorticoid Receptor (NR3C2) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Pig Mineralocorticoid Receptor (NR3C2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx512018
tested applications
ELISA
Description
Pig Mineralocorticoid Receptor (NR3C2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig Mineralocorticoid Receptor (NR3C2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Mineralocorticoid Receptor (NR3C2) |
| Reactivity | Pig |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P79404 |
| Alias | MR,MCR,MLR,NR3C2VIT,Mineralocorticoid receptor |
| Background | Elisa kits for NR3C2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Nuclear receptor subfamily 3 group C member 2 (NR3C2), also known as the mineralocorticoid receptor (MR), is a nuclear receptor that mediates the effects of mineralocorticoids, particularly aldosterone, which regulates salt and water balance, blood pressure, and electrolyte homeostasis NR3C2 is primarily expressed in the kidneys, heart, and brain, where it controls the reabsorption of sodium and water, influencing blood volume and pressure It functions by binding to aldosterone and translocating to the nucleus, where it regulates the expression of genes involved in electrolyte balance and fluid retention NR3C2 is essential for maintaining blood pressure and regulating the body's response to dehydration and salt imbalances Dysregulation of NR3C2 has been linked to various cardiovascular and renal disorders, including hypertension, heart failure, and kidney disease Overactivation of MR signaling can lead to fluid retention and hypertension, while decreased activity can result in conditions like hypoaldosteronism In addition, MR is a target for drugs such as mineralocorticoid antagonists, which are used to treat conditions like heart failure and hypertension
Related Products
Human Nr3c2(Mineralocorticoid receptor) ELISA Kit
Ver Producto
Mouse Nr3c2(Mineralocorticoid receptor) ELISA Kit
Ver Producto