Pig Integrin Beta 2 (ITGB2) ELISA Kit

Este producto es parte de ITGB2 - integrin subunit beta 2
Pig Integrin Beta 2 (ITGB2) ELISA Kit
715€ (96 tests)

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Name
Pig Integrin Beta 2 (ITGB2) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx512308
Tested Applications
ELISA

Description

Pig Integrin Beta 2 (ITGB2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig Integrin Beta 2 (ITGB2) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Integrin Beta 2 (ITGB2)
Reactivity
Pig
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P53714
Alias
LAD,CD18,MF17,MFI7,LCAMB,LFA-1,MAC-1,Integrin beta-2,Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta
Background
Elisa Kits for: ITGB2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

ITGB2, or integrin subunit beta 2, is a protein that plays a central role in leukocyte adhesion and signaling, facilitating the immune system's response to infections and inflammation. ITGB2, also known as CD18, is part of the integrin family, which consists of transmembrane receptors involved in cell-cell and cell-extracellular matrix (ECM) interactions. Integrins are heterodimeric proteins formed by the association of alpha (α) and beta (β) subunits. In particular, ITGB2 pairs with various alpha integrin subunits to form key receptors known as beta-2 integrins. Beta-2 integrins are primarily expressed on leukocytes (white blood cells) and are essential for mediating cell adhesion, migration, phagocytosis, and immune surveillance. The four major integrins that involve ITGB2 are LFA-1 (αLβ2, CD11a/CD18), Mac-1 (αMβ2, CD11b/CD18), gp150/95 (αXβ2, CD11c/CD18), and αDβ2 (CD11d/CD18). These integrins are vital for the immune system's ability to respond to infections and regulate inflammation.

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