Pig Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit

Este producto es parte de GNRHR - Gonadotropin Releasing Hormone Receptor
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715€ (96 tests)

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935106861
info@markelab.com
name
Pig Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx518137
tested applications
ELISA

Description

Pig Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig Gonadotropin-releasing hormone receptor concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetGonadotropin Releasing Hormone Receptor (GNRHR)
ReactivityPig
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.312 ng/ml - 20 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-12 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDP49922
AliasGNRHR,luteinizing hormone-releasing hormone (LHRH) receptor,GNRHR1,LHRH receptor,Type I GnRHR,gnRH receptor,GnRH-R,GnRH I receptor,GnRHR,luliberin receptor ,LHRHR, GRHR, HH7, LHRHR,GnRH1 receptor
BackgroundElisa kits for GNRHR
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

GNRHR is a G protein-coupled receptor (GPCR) expressed primarily in the anterior pituitary gland, where it binds gonadotropin-releasing hormone (GnRH). Upon activation, GNRHR stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which regulate gonadal function, steroidogenesis, and gametogenesis. GNRHR signaling occurs through Gq/11 proteins, activating phospholipase C (PLC), increasing intracellular calcium, and stimulating protein kinase C (PKC). It plays a central role in reproductive physiology, controlling the menstrual cycle in females and testosterone production in males. Mutations in GNRHR are linked to disorders such as hypogonadotropic hypogonadism, characterized by delayed puberty and infertility. GNRHR is also expressed in extra-pituitary tissues and certain cancers, such as breast, prostate, and ovarian cancers, where it regulates cell proliferation and survival. Therapeutically, GnRH agonists and antagonists are used to treat hormone-dependent conditions, including infertility, endometriosis, and cancers. GNRHR remains a critical target in reproductive medicine and oncology.

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