Pig Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit

Este producto es parte de GNRHR - Gonadotropin Releasing Hormone Receptor
Pig Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits GNRHR

proveedor

Abbexa

reference

abx518137

Tested Applications

ELISA

reactivity

Pig

status

RUO

clonality

Descripción

Pig Gonadotropin Releasing Hormone Receptor (GNRHR) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig Gonadotropin-releasing hormone receptor concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

GNRHR is a G protein-coupled receptor (GPCR) expressed primarily in the anterior pituitary gland, where it binds gonadotropin-releasing hormone (GnRH). Upon activation, GNRHR stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which regulate gonadal function, steroidogenesis, and gametogenesis. GNRHR signaling occurs through Gq/11 proteins, activating phospholipase C (PLC), increasing intracellular calcium, and stimulating protein kinase C (PKC). It plays a central role in reproductive physiology, controlling the menstrual cycle in females and testosterone production in males. Mutations in GNRHR are linked to disorders such as hypogonadotropic hypogonadism, characterized by delayed puberty and infertility. GNRHR is also expressed in extra-pituitary tissues and certain cancers, such as breast, prostate, and ovarian cancers, where it regulates cell proliferation and survival. Therapeutically, GnRH agonists and antagonists are used to treat hormone-dependent conditions, including infertility, endometriosis, and cancers. GNRHR remains a critical target in reproductive medicine and oncology.

Características del producto

category

ELISA Kits


immunogen target

Gonadotropin Releasing Hormone Receptor (GNRHR)


reactivity

Pig


test range

0.312 ng/ml - 20 ng/ml


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

GNRHR,luteinizing hormone-releasing hormone (LHRH) receptor,GNRHR1,LHRH receptor,Type I GnRHR,gnRH receptor,GnRH-R,GnRH I receptor,GnRHR,luliberin receptor ,LHRHR, GRHR, HH7, LHRHR,GnRH1 receptor


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

GNRHR


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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