Pig Complement Fragment C3a (C3a) CLIA Kit
845€ (96 tests)
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935106861
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name
Pig Complement Fragment C3a (C3a) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx491426
tested applications
CLIA
Description
Pig Complement C3a Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Complement Fragment C3a (C3a) |
| Reactivity | Pig |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | < 11.2 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ASP,C3a,C3b,AHUS5,ARMD9,CPAMD1,HEL-S-62p,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 |
| Background | CLIA Kits C3 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Complement C3 is a central component of the complement system, an essential part of the innate immune response that aids in the clearance of pathogens and the regulation of inflammation C3 is involved in all three complement pathways (classical, alternative, and lectin), playing a critical role in immune defense by promoting opsonization, cell lysis, and inflammation activation Upon cleavage into C3a and C3b, C3a acts as an inflammatory mediator, and C3b binds to pathogens to mark them for destruction by phagocytes Complement C3 deficiency or dysfunction is associated with various autoimmune diseases, such as systemic lupus erythematosus (SLE), and with susceptibility to infections C3 is also involved in the regulation of adaptive immunity, influencing antibody production and T-cell responses Its role in inflammation, pathogen clearance, and immune system regulation highlights its importance in maintaining immune balance and tissue homeostasis
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