Pig Apoptosis Regulator Bcl-2 (BCL2) Protein

Este producto es parte de BCL2 - BCL2 apoptosis regulator
Pig Apoptosis Regulator Bcl-2 (BCL2) Protein

Pida mas información

935106861

info@markelab.com

Precio

2112.5€ (1 mg)

Protein BCL2

proveedor

Abbexa

reference

abx652647

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Pig B-Cell Leukemia/Lymphoma 2 (Bcl2) Protein is a Recombinant Pig protein expressed in E. coli.


Background

BCL2 apoptosis regulator (BCL2) is a key anti-apoptotic protein that plays a central role in regulating cell survival by preventing mitochondrial-mediated apoptosis BCL2 functions by inhibiting the release of pro-apoptotic factors, such as cytochrome c, from the mitochondria, thus preventing caspase activation and cell death It is highly expressed in various tissues, particularly in immune cells and neurons, where it protects against apoptosis and supports cell longevity Dysregulation of BCL2 expression has been associated with several diseases, including cancer, where its overexpression allows tumor cells to evade cell death, contributing to tumor progression and resistance to therapy BCL2 is also implicated in neurodegenerative diseases, where its dysfunction can lead to excessive neuronal death BCL2 interacts with other members of the Bcl-2 family, including pro-apoptotic proteins like BAX, to finely tune apoptotic signaling and maintain cellular homeostasis Its role in regulating apoptosis and survival pathways makes BCL2 a critical factor in development, aging, and disease management

Características del producto

category

Proteins and Peptides


origin

Pig


host

E. coli


immunogen target

Apoptosis Regulator Bcl-2 (BCL2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized


tested applications

WB, SDS-PAGE


size 1

1 mg


size 2

5 mg


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

BCL2


dry ice

No


availability

Shipped within 1-2 months.


alias

Bcl-2,PPP1R50,B-Cell CLL/Lymphoma 2


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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