Pig Apoptosis Regulator Bcl-2 (BCL2) Protein
Pida mas información
935106861
info@markelab.com
Precio
2112.5€ (1 mg)
Protein BCL2
proveedor
Abbexareference
abx652647Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Pig B-Cell Leukemia/Lymphoma 2 (Bcl2) Protein is a Recombinant Pig protein expressed in E. coli.
Background
BCL2 apoptosis regulator (BCL2) is a key anti-apoptotic protein that plays a central role in regulating cell survival by preventing mitochondrial-mediated apoptosis BCL2 functions by inhibiting the release of pro-apoptotic factors, such as cytochrome c, from the mitochondria, thus preventing caspase activation and cell death It is highly expressed in various tissues, particularly in immune cells and neurons, where it protects against apoptosis and supports cell longevity Dysregulation of BCL2 expression has been associated with several diseases, including cancer, where its overexpression allows tumor cells to evade cell death, contributing to tumor progression and resistance to therapy BCL2 is also implicated in neurodegenerative diseases, where its dysfunction can lead to excessive neuronal death BCL2 interacts with other members of the Bcl-2 family, including pro-apoptotic proteins like BAX, to finely tune apoptotic signaling and maintain cellular homeostasis Its role in regulating apoptosis and survival pathways makes BCL2 a critical factor in development, aging, and disease management
Características del producto
category
Proteins and Peptides
origin
Pig
host
E. coli
immunogen target
Apoptosis Regulator Bcl-2 (BCL2)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
1 mg
size 2
5 mg
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
BCL2
dry ice
No
availability
Shipped within 1-2 months.
alias
Bcl-2,PPP1R50,B-Cell CLL/Lymphoma 2
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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