Pig Annexin A1 (ANXA1) Protein
351€ (50 µg)
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name
Pig Annexin A1 (ANXA1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065362
tested applications
WB, SDS-PAGE
Description
Recombinant Annexin A1 (ANXA1) is a recombinant Pig protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A1 (ANXA1) |
| Host | E. coli |
| Origin | Pig |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 20.6 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu208-Glu336 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P19619 |
| Alias | Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9 |
| Background | Protein ANXA1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ANXA1 is a calcium-dependent phospholipid-binding protein that plays a critical role in anti-inflammatory responses and cell signaling. It regulates the resolution of inflammation by inhibiting the release of pro-inflammatory mediators and modulating the activity of phospholipase A2 (PLA2). ANXA1 also influences cellular processes such as apoptosis, phagocytosis, and membrane repair. It is expressed in various tissues, including immune cells like neutrophils and macrophages, where it supports immune suppression and tissue repair. Dysregulation of ANXA1 has been implicated in cancer progression, where it can act as either a tumor suppressor or promoter depending on the context. Its anti-inflammatory and apoptotic regulatory properties highlight its therapeutic potential in inflammatory diseases, autoimmune disorders, and cancer.
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