Pig Angiopoietin-Related Protein 4 (ANGPTL4) Protein
468€ (50 µg)
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935106861
info@markelab.com
name
Pig Angiopoietin-Related Protein 4 (ANGPTL4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065340
tested applications
WB, SDS-PAGE
Description
Pig ANGPTL4 is a recombinant Pig protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Angiopoietin-Related Protein 4 (ANGPTL4) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Asp227-Trp389 Tag: N-terminal His tag |
| Origin | Pig |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 19.7 kDa Observed MW (SDS-PAGE): 19 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q2TNK5 |
| Alias | ARP4,FIAF,HARP,HFARP,NL2 |
| Background | Protein ANGPTL4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
ANGPTL4 is a secreted glycoprotein that plays key roles in lipid metabolism, angiogenesis, and inflammation. ANGPTL4 functions as an inhibitor of lipoprotein lipase (LPL), regulating triglyceride hydrolysis and fatty acid release, particularly during fasting and energy deprivation. It is expressed in adipose tissue, liver, and muscle, where it coordinates energy balance and lipid transport. ANGPTL4 also modulates angiogenesis by inhibiting endothelial cell proliferation and migration, making it a negative regulator of vascular growth. In cancer, ANGPTL4 has context-dependent roles, promoting metastasis by enhancing tumor cell migration and vascular permeability while inhibiting angiogenesis in certain conditions. Elevated ANGPTL4 levels are associated with obesity, diabetes, and atherosclerosis, where it contributes to dyslipidemia and chronic inflammation. Its ability to regulate lipid metabolism, angiogenesis, and inflammation makes ANGPTL4 a potential target for treating metabolic disorders, cardiovascular disease, and cancer.
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