Phosphopantothenoylcysteine decarboxylase (PPCDC) Antibody (HRP)
169€ (20 µg)
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Name
Phosphopantothenoylcysteine decarboxylase (PPCDC) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx344175
Tested Applications
ELISA
Description
Phosphopantothenoylcysteine decarboxylase (PPCDC) Antibody (HRP) is a Rabbit Polyclonal antibody conjugated to HRP for the detection of Human PPCDC.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Phosphopantothenoylcysteine decarboxylase (PPCDC) Immunogen: Recombinant Human Phosphopantothenoylcysteine decarboxylase protein (51-183 AA) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96CD2 |
| Gene ID | 60490 |
| OMIM | 609854 |
| Alias | PPAR,NR1C1,Hppar,PPARalpha,PPAR-alpha,Nuclear receptor subfamily 1 group C member 1 |
| Background | Antibody anti-PPARA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Peroxisome proliferator activated receptor alpha (PPARA) is a nuclear hormone receptor that plays a critical role in the regulation of lipid metabolism, inflammation, and energy homeostasis PPARA is primarily expressed in tissues involved in fatty acid metabolism, such as the liver, heart, and skeletal muscle, where it regulates the transcription of genes involved in the breakdown of fatty acids and lipids The receptor functions by binding to specific ligands, such as fatty acids and fibrates, which activate PPARA and induce the expression of genes involved in lipid catabolism, mitochondrial biogenesis, and oxidative stress response PPARA is also involved in regulating glucose metabolism and insulin sensitivity, making it a key player in metabolic diseases like diabetes and obesity Dysregulation of PPARA has been linked to various disorders, including cardiovascular diseases, metabolic syndrome, and fatty liver disease PPARA's role in regulating inflammation further highlights its therapeutic potential in conditions characterized by chronic inflammation, including atherosclerosis and neurodegenerative diseases
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