Phospholipase C Delta 4 (PLCD4) Antibody
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Description
PLCD4 Antibody is a Rabbit Polyclonal against PLCD4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Phospholipase C Delta 4 (PLCD4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BRC7 |
| Gene ID | 84812 |
| NCBI Accession | NP_116115.1, NM_032726.3 |
| OMIM | 605939 |
| Background | Antibody anti-PLCD4 |
| Status | RUO |
Descripción
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Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
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Phospholipase C Delta 4 (PLCD4) Antibody
PLCD4 Antibody is a Rabbit Polyclonal Antibody against PLCD4.
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Phospholipase C Delta 4 (PLCD4) Antibody
PLCD4 Antibody is a Rabbit Polyclonal against PLCD4.
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