Phospholipase C Delta 4 (PLCD4) Antibody

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Description
PLCD4 Antibody is a Rabbit Polyclonal against PLCD4.
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Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | Phospholipase C Delta 4 (PLCD4)  | 
| Host | Rabbit  | 
| Reactivity | Human  | 
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Polyclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG  | 
| Purity | > 95%  | 
| Purification | Purified by Protein G.  | 
| Size 1 | 20 µg  | 
| Size 2 | 50 µg  | 
| Size 3 | 100 µg  | 
| Size 4 | 200 µg  | 
| Size 5 | 1 mg  | 
| Form | Liquid  | 
| Tested Applications | ELISA, IHC  | 
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | Q9BRC7  | 
| Gene ID | 84812  | 
| NCBI Accession | NP_116115.1, NM_032726.3  | 
| OMIM | 605939  | 
| Background | Antibody anti-PLCD4  | 
| Status | RUO  | 
Descripción
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Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
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Phospholipase C Delta 4 (PLCD4) Antibody
PLCD4 Antibody is a Rabbit Polyclonal Antibody against PLCD4.
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Phospholipase C Delta 4 (PLCD4) Antibody
PLCD4 Antibody is a Rabbit Polyclonal against PLCD4.
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