Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP] (PCK1) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP] (PCK1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455227
tested applications
ELISA, WB, IHC
Description
Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP] (PCK1) Antibody is a Rabbit polyclonal antibody for the detection of Human Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP] (PCK1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP] (PCK1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P35558 |
| Gene ID | 5105 |
| NCBI Accession | NP_002582.3 |
| Background | Antibody anti-PCK1 |
| Status | RUO |
Descripción
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This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
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