PHD Finger Protein 7 (PHF7) Antibody (FITC)

Este producto es parte de PHF - PHD finger protein
PHD Finger Protein 7 (PHF7) Antibody (FITC)

Pida mas información

935106861

info@markelab.com

Precio

162.5€ (20 µg)

Antibody anti-PHF7

proveedor

Abbexa

reference

abx344103

Tested Applications

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

PHD Finger Protein 7 (PHF7) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human PHF7.


Background

PHF7 is a histone-binding protein containing a PHD finger domain that recognizes methylated histones, particularly H3K4me3, to regulate transcriptional activation. PHF7 plays a role in spermatogenesis and male fertility by coordinating chromatin remodeling and gene expression during germ cell development. It interacts with transcriptional regulators and chromatin modifiers to activate genes essential for germ cell differentiation and meiosis. PHF7 is specifically expressed in testicular tissues, where it facilitates proper gene expression programs for spermatocyte maturation. Dysregulation or mutations in PHF7 are associated with male infertility due to disrupted spermatogenesis and impaired germ cell differentiation. Knockdown studies reveal defective chromatin remodeling, reduced germ cell proliferation, and meiotic arrest, emphasizing its role in transcriptional activation, germline development, and reproductive health.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

PHD Finger Protein 7 (PHF7)


host

Rabbit


conjugation

FITC


form

Liquid


purity

> 95%


purification

Purified by Protein G chromatography.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

PHF7


dry ice

No


availability

Shipped within 5-10 working days.


alias

HSPC045, HSPC226, NYD-SP6,Testis development protein NYD-SP6


note

This product is for research use only.


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