PHD Finger Protein 7 (PHF7) Antibody (FITC)
Pida mas información
935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-PHF7
proveedor
Abbexareference
abx344103Tested Applications
reactivity
Humanstatus
RUOclonality
PolyclonalDescripción
PHD Finger Protein 7 (PHF7) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human PHF7.
Background
PHF7 is a histone-binding protein containing a PHD finger domain that recognizes methylated histones, particularly H3K4me3, to regulate transcriptional activation. PHF7 plays a role in spermatogenesis and male fertility by coordinating chromatin remodeling and gene expression during germ cell development. It interacts with transcriptional regulators and chromatin modifiers to activate genes essential for germ cell differentiation and meiosis. PHF7 is specifically expressed in testicular tissues, where it facilitates proper gene expression programs for spermatocyte maturation. Dysregulation or mutations in PHF7 are associated with male infertility due to disrupted spermatogenesis and impaired germ cell differentiation. Knockdown studies reveal defective chromatin remodeling, reduced germ cell proliferation, and meiotic arrest, emphasizing its role in transcriptional activation, germline development, and reproductive health.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
PHD Finger Protein 7 (PHF7)
host
Rabbit
conjugation
FITC
form
Liquid
purity
> 95%
purification
Purified by Protein G chromatography.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
PHF7
dry ice
No
availability
Shipped within 5-10 working days.
alias
HSPC045, HSPC226, NYD-SP6,Testis development protein NYD-SP6
uniprot id
note
This product is for research use only.
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