Period Circadian Protein Homolog 2 (PER2) Antibody

260€ (50 µg)
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935106861
info@markelab.com
name
Period Circadian Protein Homolog 2 (PER2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx376791
tested applications
ELISA, WB, IHC
Description
Period Circadian Protein Homolog 2 (PER2) Antibody is a Rabbit polyclonal antibody for the detection of Human Period Circadian Protein Homolog 2 (PER2).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Period Circadian Protein Homolog 2 (PER2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15055 |
| Gene ID | 8864 |
| NCBI Accession | NP_073728.1 |
| Background | Antibody anti-PER2 |
| Status | RUO |
Descripción
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PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.
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