Peptidyl-Prolyl Cis-Trans Isomerase FKBP8 (FKBP8) Antibody
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Description
FKBP8 Antibody is a Goat Polyclonal antibody against FKBP8.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Peptidyl-Prolyl Cis-Trans Isomerase FKBP8 (FKBP8) |
| Host | Goat |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 23770, 14232, 290652 |
| NCBI Accession | NP_036313.3 |
| Background | Antibody anti-FKBP8 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
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Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
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