PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) Antibody
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Description
PASK Antibody is a Rabbit Polyclonal against PASK.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC063585 |
| Background | Antibody anti-PASK |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
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PASK antibody
Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions(oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation.
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PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) Antibody
PASK Antibody is a Rabbit Polyclonal Antibody against PASK.
Ver Producto
PAS Domain-Containing Serine/threonine-Protein Kinase (PASK) Antibody
PASK Antibody is a Rabbit Polyclonal against PASK.
Ver Producto