E3 Ubiquitin-Protein Ligase Parkin (PRKN) Antibody (HRP)
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Description
PRKN Antibody (HRP) is a Rabbit Polyclonal against PRKN conjugated to HRP.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | E3 Ubiquitin-Protein Ligase Parkin (PRKN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O60260 |
| Gene ID | 5071 |
| NCBI Accession | NP_004553.2, NM_004562.2 |
| OMIM | 168600 |
| Background | Antibody anti-PARKN |
| Status | RUO |
Descripción
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E3 Ubiquitin-Protein Ligase Parkin (PRKN) Antibody
PRKN Antibody is a Rabbit Polyclonal antibody against PRKN. The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support.
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