Paired Box Protein Pax-9 (PAX9) Protein
234€ (2 µg)
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935106861
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name
Paired Box Protein Pax-9 (PAX9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262710
tested applications
SDS-PAGE
Description
PAX9 is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | PAX9 |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P55771 |
| Alias | STHAG3 |
| Background | Protein PAX9 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
PAX9 is a transcription factor critical for embryonic development, particularly in skeletal and craniofacial formation, tooth development, and pharyngeal arch patterning. It regulates the expression of genes essential for tooth morphogenesis, including odontogenesis, ensuring the correct formation of dental structures such as molars and incisors. Mutations in PAX9 lead to oligodontia, a condition characterized by the congenital absence of multiple teeth, and are also associated with cleft palate and jaw malformations. PAX9 interacts with other transcription factors like MSX1 to coordinate craniofacial and dental development. In knockout models, PAX9 deficiency results in arrested tooth development, defective craniofacial structures, and impaired skeletal patterning. Its essential role in epithelial-mesenchymal interactions during organogenesis underscores its importance in tissue-specific development, tooth regeneration, and congenital anomalies.
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Paired Box Protein Pax-9 (PAX9) Antibody
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 9 gene is unknown but it may involve development of stratified squamous epithelia as well as various organs and skeletal elements.
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