Paired Box Protein Pax-9 (PAX9) Antibody
221€ (50 µg)
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Name
Paired Box Protein Pax-9 (PAX9) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx329734
Tested Applications
ELISA, WB
Description
PAX9 Antibody is a Rabbit Polyclonal against PAX9.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Paired Box Protein Pax-9 (PAX9) Immunogen: Synthesized peptide derived from the Internal region of human Pax-9. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/5000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55771 |
| Gene ID | 5083 |
| Alias | STHAG3 |
| Background | Antibody anti-PAX9 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
PAX9 is a transcription factor critical for embryonic development, particularly in skeletal and craniofacial formation, tooth development, and pharyngeal arch patterning. It regulates the expression of genes essential for tooth morphogenesis, including odontogenesis, ensuring the correct formation of dental structures such as molars and incisors. Mutations in PAX9 lead to oligodontia, a condition characterized by the congenital absence of multiple teeth, and are also associated with cleft palate and jaw malformations. PAX9 interacts with other transcription factors like MSX1 to coordinate craniofacial and dental development. In knockout models, PAX9 deficiency results in arrested tooth development, defective craniofacial structures, and impaired skeletal patterning. Its essential role in epithelial-mesenchymal interactions during organogenesis underscores its importance in tissue-specific development, tooth regeneration, and congenital anomalies.
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