Paired Box Gene 9 (PAX9) Antibody

Este producto es parte de PAX - Paired box protein Pax
Product Graph
819€ (1 ml)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Paired Box Gene 9 (PAX9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx173939
tested applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Paired Box Gene 9 (PAX9)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Please enquire.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
STHAG3
Background
Antibody anti-PAX9
Status
RUO

Descripción

PAX9 is a transcription factor critical for embryonic development, particularly in skeletal and craniofacial formation, tooth development, and pharyngeal arch patterning. It regulates the expression of genes essential for tooth morphogenesis, including odontogenesis, ensuring the correct formation of dental structures such as molars and incisors. Mutations in PAX9 lead to oligodontia, a condition characterized by the congenital absence of multiple teeth, and are also associated with cleft palate and jaw malformations. PAX9 interacts with other transcription factors like MSX1 to coordinate craniofacial and dental development. In knockout models, PAX9 deficiency results in arrested tooth development, defective craniofacial structures, and impaired skeletal patterning. Its essential role in epithelial-mesenchymal interactions during organogenesis underscores its importance in tissue-specific development, tooth regeneration, and congenital anomalies.

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