PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.
Primary Antibodies
Polyclonal
Human
P21 Protein Activated Kinase 2 (PAK2)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
PBS containing 0.09% sodium azide.
80 µl
400 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
PAK2
No
Shipped within 5-10 working days.
This product is for research use only.
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear ...
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Ver másPAK2 Antibody is a Rabbit Polyclonal Antibody against PAK2.
175€ (20 µl)
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