OX-2 Membrane Glycoprotein (CD200) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
OX-2 Membrane Glycoprotein (CD200) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx414732
tested applications
IHC, IF/ICC, FCM, IP
Description
OX-2 Membrane Glycoprotein (CD200) Antibody is a Mouse Monoclonal antibody against OX-2 Membrane Glycoprotein (CD200).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | OX-2 Membrane Glycoprotein (CD200) |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 100 µg |
| Size 2 | 250 µg |
| Form | Liquid |
| Tested Applications | IHC, IF/ICC, FCM, IP |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04218 |
| Alias | OX-2 membrane glycoprotein,MRC,MOX1,MOX2,OX-2,My033 |
| Background | Antibody anti-CD200 |
| Status | RUO |
| Note | Concentration: 1.0 mg/ml - |
Descripción
CD200, also known as OX-2, is a membrane glycoprotein primarily involved in immune modulation. It is a member of the immunoglobulin superfamily and is widely expressed on various cell types, including neurons, epithelial cells, endothelial cells, thymocytes, and certain immune cells like B cells, T cells, and dendritic cells. CD200 plays a critical role in maintaining immune homeostasis by binding to its receptor, CD200R, predominantly on myeloid cells and some T cells. This interaction triggers an inhibitory signaling pathway that dampens immune responses, helping to prevent overactivation of the immune system and the development of autoimmunity. CD200 is implicated in a range of physiological and pathological processes, including immune tolerance, regulation of inflammation, tumor immunity, and protection of tissues from immune-mediated damage.
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