Osteopontin (SPP1) Antibody

292.5€ (50 µg)
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935106861
info@markelab.com
name
Osteopontin (SPP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx210139
tested applications
ELISA, WB, IHC
Description
Osteopontin Antibody is a Mouse Monoclonal against Osteopontin.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Osteopontin (SPP1) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/50 - 1/500. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2a |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin 300 and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P10451 |
Gene ID | 6696 |
NCBI Accession | NP_000573.1 |
OMIM | 166490 |
Background | Antibody anti-SPP1 |
Status | RUO |
Descripción
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Osteopontin(OPN), also known as SPP1, is a secreted glycophosphoprotein that belongs to the small integrin-binding ligand N-linked glycoprotein(SIBLING) family. Originally isolated from bone, OPN has been found in kidney, vascular tissues, biological fluids, and various tumor tissues(PMID: 15138464; 16406521). OPN can interact with CD44 and integrins and regulate diverse biological processes. It has a multifaceted role in bone development and remodeling, and is also involved in the inflammatory and immune response, oncogenesis and cancer progression.
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