Origin Recognition Complex Subunit 6 (ORC6) Protein

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234€ (2 µg)

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935106861
info@markelab.com
name
Origin Recognition Complex Subunit 6 (ORC6) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx263384
tested applications
SDS-PAGE

Description

ORC6 is a recombinant protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
ORC6
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
100 µg
Form
Liquid
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
UniProt ID
Q9Y5N6
Background
Protein ORC6
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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Component of the origin recognition complex(ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

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Origin Recognition Complex Subunit 6 (ORC6) Antibody

ORC6 Antibody is a Rabbit Polyclonal antibody against ORC6. The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.

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