Opsin 1, Short Wave Sensitive (OPN1SW) Antibody

Background

OPN1SW is an opsin found in the cone cells of the retina, responsible for detecting short wavelengths of light, typically in the blue region of the visible spectrum. It is activated by light with wavelengths ranging from approximately 420–440 nm. OPN1SW plays a crucial role in human color vision, particularly in the perception of blue hues. Like other opsins, OPN1SW works by converting light into an electrical signal that is sent to the brain for processing. This opsin is essential for maintaining the trichromatic vision system in humans, which enables the discrimination of colors in the blue portion of the visible spectrum. Mutations in the OPN1SW gene can result in color vision deficiencies, such as blue-yellow color blindness, where individuals struggle to distinguish between blue and yellow hues. The study of OPN1SW is important for understanding visual perception and the genetic basis of color vision defects.