Nucleoporin 93 (NUP93) Antibody
221€ (50 µg)
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Name
Nucleoporin 93 (NUP93) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx327868
Tested Applications
ELISA, WB
Description
NUP93 Antibody is a Rabbit Polyclonal against NUP93.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin 93 (NUP93) Immunogen: Synthesized peptide derived from the Internal region of human Nup93. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N1F7 |
| Gene ID | 9688 |
| Alias | nucleoporin 93kDa, nuclear pore complex protein Nup93 |
| Background | Antibody anti-NUP93 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 93 (NUP93) is another integral component of the nuclear pore complex, playing a critical role in the maintenance and function of the nuclear envelope NUP93 is involved in the structural formation of the nuclear pore and facilitates the transport of molecules, such as RNA and proteins, across the nuclear membrane It participates in the organization of the nuclear pore complex and is essential for the proper function of nucleocytoplasmic transport, ensuring that gene expression and cellular responses are maintained NUP93 also interacts with other nucleoporins to form the scaffold for the central pore and is involved in regulating the selective passage of molecules across the nuclear envelope Dysregulation of NUP93 has been associated with various diseases, including cancers, where defects in nuclear transport contribute to cellular dysfunction, uncontrolled growth, and metastasis Additionally, NUP93 plays a role in cellular signaling and maintaining nuclear integrity under stress conditions, highlighting its importance in preserving cellular homeostasis and response to environmental changes
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