Nucleoporin 35 (NUP35) Antibody
169€ (20 µg)
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Name
Nucleoporin 35 (NUP35) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx309235
Tested Applications
ELISA, WB
Description
NUP35 Antibody is a Rabbit Polyclonal against NUP35.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin 35 (NUP35) Immunogen: Recombinant human Nucleoporin NUP53 protein (6-305AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFH5 |
| Gene ID | 129401 |
| NCBI Accession | NP_001274513.1, NM_001287584.1, NP_001274514.1, NM_001287585.1, NP_612142.2, NM_138285.4 |
| OMIM | 608140 |
| Alias | MP44,NP44,MP-44,NUP53,35 kDa nucleoporin,Mitotic phosphoprotein 44,Nucleoporin NUP53 |
| Background | Antibody anti-NUP35 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 35 (NUP35) is a component of the nuclear pore complex, which serves as the gateway between the nucleus and the cytoplasm NUP35 plays an essential role in the structural integrity of the nuclear pore and in regulating the trafficking of molecules, particularly RNA and proteins, across the nuclear envelope As a nucleoporin, NUP35 participates in the formation of the nuclear pore complex, which facilitates selective transport and ensures proper cellular signaling and gene expression It also helps maintain nuclear-cytoplasmic communication, influencing cellular processes such as cell division, transcription, and gene regulation Dysregulation of NUP35 has been implicated in several diseases, including cancers and neurodegenerative disorders, where defective nuclear transport and nucleoporin function contribute to disease progression