Nucleoporin 160 (NUP160) Antibody
312€ (60 µl)
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Name
Nucleoporin 160 (NUP160) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx124217
Tested Applications
WB
Description
NUP160 Antibody is a Rabbit Polyclonal Antibody against NUP160.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleoporin 160 (NUP160) Immunogen: Recombinant fusion protein corresponding to human NUP160 |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 24 kDa/55 kDa/162 kDa Observed MW: 150 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12769 |
| Gene ID | 23279 |
| NCBI Accession | NP_056046.1 |
| Alias | NPHS19,nucleoporin 160kDa,Nuclear pore complex protein Nup160 |
| Background | Antibody anti-NUP160 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleoporin 160 (NUP160) is a large and essential component of the nuclear pore complex, contributing to the overall architecture and function of the NPC NUP160 is involved in the regulation of nuclear-cytoplasmic transport, particularly in the trafficking of RNA and proteins that are crucial for gene expression, protein synthesis, and cellular signaling It helps maintain the structure of the nuclear pore and facilitates the passage of macromolecules across the nuclear envelope, ensuring the efficiency of molecular exchange NUP160 plays a critical role in regulating the cell cycle, particularly in processes such as mitosis, where it helps control the localization of key regulatory proteins Additionally, NUP160 is linked to the regulation of immune responses and tissue repair, making it an important factor in the body's response to cellular stress and injury Dysregulation of NUP160 has been associated with several diseases, including cancers and immune system disorders, where altered nuclear transport contributes to pathological changes in cell growth, gene regulation, and immune function