Notch Homolog 3 (NOTCH3) Antibody

312€ (100 µl)
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935106861
info@markelab.com
name
Notch Homolog 3 (NOTCH3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx132878
tested applications
WB, IHC, IF/ICC
Description
Notch Homolog 3 (NOTCH3) Antibody is a Rabbit Polyclonal antibody for the detection of Notch Homolog 3 (NOTCH3).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Notch Homolog 3 (NOTCH3) |
Host | Rabbit |
Reactivity | Mouse |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen-specific affinity chromatography followed by Protein A affinity chromatography. |
Size 1 | 100 µl |
Size 2 | 200 µl |
Size 3 | 1 ml |
Form | Liquid |
Tested Applications | WB, IHC, IF/ICC |
Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | CADASIL,CADASIL1,CASIL,IMF2,LMNS,notch receptor 3 |
Background | Antibody anti-NOTCH3 |
Status | RUO |
Note | Concentration: 0.5 mg/ml - |
Descripción
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NOTCH3 antibody
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
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