Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 3 (NMNAT3) Antibody (FITC)

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Description
NMNAT3 Antibody (FITC) is a Rabbit Polyclonal against NMNAT3 conjugated to FITC.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 3 (NMNAT3) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | FITC |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q96T66 |
Gene ID | 349565 |
NCBI Accession | NP_001186976.1, NM_001200047.2, NP_001307440.1, NM_001320511.1 |
OMIM | 608702 |
Background | Antibody anti-NMNAT3 |
Status | RUO |
Descripción
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NMNAT3 antibody
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide(NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide(NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate(TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD(+), NADH, NaAD, nicotinic acid adenine dinucleotide phosphate(NHD), nicotinamide guanine dinucleotide(NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following injury.
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