NF-Kappa-B Inhibitor Zeta (NFKBIZ) Antibody
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Description
NF-Kappa-B Inhibitor Zeta (NFKBIZ) Antibody is a Rabbit polyclonal antibody for the detection of Human NF-Kappa-B Inhibitor Zeta (NFKBIZ).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | NF-Kappa-B Inhibitor Zeta (NFKBIZ) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BYH8 |
| Gene ID | 64332 |
| NCBI Accession | NP_001005474.1 |
| Background | Antibody anti-NFKBIZ |
| Status | RUO |
Descripción
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NFKBIZ antibody
Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis(By similarity).
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NFKBIZ Antibody is a Rabbit Polyclonal against NFKBIZ.
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