Neuroplastin (NPTN) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Neuroplastin (NPTN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx146042
tested applications
ELISA, WB
Description
NPTN Antibody is a Rabbit Polyclonal against NPTN.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuroplastin (NPTN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y639 |
| Gene ID | 27020 |
| NCBI Accession | NM_001161363.1, NM_001161364.1, NM_012428.3, NM_017455.3 |
| OMIM | 612820 |
| Alias | GP55,GP65,SDR1,np55,np65,SDFR1, Stromal cell-derived receptor 1 |
| Background | Antibody anti-NPTN |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
Neuroplastin (NPTN) is a member of the immunoglobulin superfamily and plays a crucial role in synaptic plasticity, learning, and memory. The NPTN gene is located on chromosome 15q24 and encodes two main isoforms through alternative splicing: Neuroplastin-55 (Np55) and Neuroplastin-65 (Np65). These isoforms are integral membrane proteins expressed predominantly in the brain, although they are also present in other tissues. Neuroplastin is involved in various cellular processes, including cell adhesion, signal transduction, and calcium homeostasis. Its expression and function are essential for the proper formation and maintenance of synaptic connections, making it a key player in neurodevelopmental and neuropsychiatric disorders.
