Neuroplastin (NPTN) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Neuroplastin (NPTN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027055
tested applications
ELISA, WB
Description
This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neuroplastin (NPTN) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y639 |
| Gene ID | 27020 |
| OMIM | 612820 |
| Alias | GP55,GP65,SDR1,np55,np65,SDFR1, Stromal cell-derived receptor 1 |
| Background | Antibody anti-NPTN |
| Status | RUO |
Descripción
Neuroplastin (NPTN) is a member of the immunoglobulin superfamily and plays a crucial role in synaptic plasticity, learning, and memory. The NPTN gene is located on chromosome 15q24 and encodes two main isoforms through alternative splicing: Neuroplastin-55 (Np55) and Neuroplastin-65 (Np65). These isoforms are integral membrane proteins expressed predominantly in the brain, although they are also present in other tissues. Neuroplastin is involved in various cellular processes, including cell adhesion, signal transduction, and calcium homeostasis. Its expression and function are essential for the proper formation and maintenance of synaptic connections, making it a key player in neurodevelopmental and neuropsychiatric disorders.
