Neuroplastin (NPTN) Antibody

Este producto es parte de NPTN - neuroplastin
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292.5€ (80 µl)

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935106861
info@markelab.com
name
Neuroplastin (NPTN) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx027055
tested applications
ELISA, WB

Description

This gene encodes a type I transmembrane protein belonging to the Ig superfamily. The protein is believed to be involved in cell-cell interactions or cell-substrate interactions. Alternative splicing results in multiple transcript variants. [provided by RefSeq].

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Product specifications

CategoryPrimary Antibodies
Immunogen TargetNeuroplastin (NPTN)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified through a protein A column, followed by peptide affinity purification.
Size 180 µl
Size 2400 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS containing 0.09% sodium azide.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9Y639
Gene ID27020
OMIM612820
AliasGP55,GP65,SDR1,np55,np65,SDFR1, Stromal cell-derived receptor 1
BackgroundAntibody anti-NPTN
StatusRUO

Descripción

Neuroplastin (NPTN) is a member of the immunoglobulin superfamily and plays a crucial role in synaptic plasticity, learning, and memory. The NPTN gene is located on chromosome 15q24 and encodes two main isoforms through alternative splicing: Neuroplastin-55 (Np55) and Neuroplastin-65 (Np65). These isoforms are integral membrane proteins expressed predominantly in the brain, although they are also present in other tissues. Neuroplastin is involved in various cellular processes, including cell adhesion, signal transduction, and calcium homeostasis. Its expression and function are essential for the proper formation and maintenance of synaptic connections, making it a key player in neurodevelopmental and neuropsychiatric disorders.

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