Neuronal Migration Protein Doublecortin (DCX) Antibody

442€ (100 µg)
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935106861
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name
Neuronal Migration Protein Doublecortin (DCX) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx461356
tested applications
ELISA, SPR
Description
Neuronal Migration Protein Doublecortin (DCX) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human DCX.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | Neuronal Migration Protein Doublecortin (DCX)  | 
| Host | CHO cells  | 
| Reactivity | Human  | 
| Clonality | Monoclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | VHH-8His-Cys-tag  | 
| Clone ID | Z919  | 
| Purity | > 95% (SDS-PAGE)  | 
| Purification | Purified by Protein A/G affinity chromatography.  | 
| Size 1 | 100 µg  | 
| Size 2 | 1 mg  | 
| Form | Liquid  | 
| Tested Applications | ELISA, SPR  | 
| Buffer | 0.01 M PBS, pH 7.4.  | 
| Availability | Shipped within 5-12 working days.  | 
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | O43602  | 
| Gene ID | 1641  | 
| NCBI Accession | NP_000546.2  | 
| Background | Antibody anti-DCX  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
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Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.
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