Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) Peptide

175.5€ (100 µg)
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935106861
info@markelab.com
name
Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx269806
tested applications
P-ELISA
Description
Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) Peptide is a synthetic peptide.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) |
Host | Synthetic |
Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Observed MW | Sequence Fragment: C-Terminus: C-QLGPQPEVTPKRQ |
Size 1 | 100 µg |
Form | Lyophilized Reconstitute in deionized water. |
Tested Applications | P-ELISA |
Buffer | Prior to lyophilization: Deionized water. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 4854 |
NCBI Accession | NP_000426.2 |
Alias | CADASIL,CADASIL1,CASIL,IMF2,LMNS,notch receptor 3 |
Background | Protein NOTCH3 |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
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