Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) Antibody
442€ (100 µg)
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935106861
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name
Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx461620
tested applications
ELISA
Description
Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) Antibody is a monoclonal Nanobody expressed in CHO cells for the detection of Human NOTCH3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neurogenic Locus Notch Homolog Protein 3 (NOTCH3) |
| Host | CHO cells |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | VHH-8His-Cys-tag |
| Clone ID | F146 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UM47 |
| Gene ID | 4854 |
| NCBI Accession | NP_000426.2 |
| Alias | CADASIL,CADASIL1,CASIL,IMF2,LMNS,notch receptor 3 |
| Background | Antibody anti-NOTCH3 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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NOTCH3 antibody
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).
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