Neurofascin (NFASC) Antibody
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Description
Neurofascin Antibody is a Goat Polyclonal antibody against Neurofascin.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Neurofascin (NFASC) |
| Host | Goat |
| Reactivity | Human |
| Recommended Dilution | P-ELISA: 1/16000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 23114, 269116, 116690 |
| NCBI Accession | NP_001005388.2, NP_001153803.1, NP_001153804.1, NP_055905.2 |
| Alias | NF,NRCAML,NEDCPMD,KIAA0756 |
| Background | Antibody anti-NFASC |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
Neurofascin (NFASC) is a cell adhesion molecule crucial for the development and maintenance of the nervous system. It is part of the L1 family of cell adhesion molecules, which are integral membrane proteins involved in cell-cell adhesion processes. Neurofascin plays a pivotal role in the formation and function of the nodes of Ranvier and the initial segments of axons, both of which are critical for the proper conduction of electrical impulses along neurons. The NFASC gene, located on chromosome 1q32.1, encodes several isoforms of neurofascin through alternative splicing. These isoforms have distinct but overlapping functions in neural development and synaptic plasticity.
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