Neurobeachin (NBEA) Antibody

Este producto es parte de NBEA - neurobeachin
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416€ (200 µl)

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935106861
info@markelab.com
name
Neurobeachin (NBEA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431838
tested applications
P-ELISA, IHC

Description

Neurobeachin Antibody is a Goat Polyclonal antibody against Neurobeachin.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetNeurobeachin (NBEA)
HostGoat
ReactivityHuman
Recommended DilutionP-ELISA: 1/4000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1200 µl
FormLiquid
Tested ApplicationsP-ELISA, IHC
BufferTris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
Gene ID26960, 26422
NCBI AccessionNP_056493.3, NP_001191126.1
AliasBCL8B,LYST2,NEDEGE,Protein BCL8B,Lysosomal-trafficking regulator 2
BackgroundAntibody anti-NBEA
StatusRUO
NoteConcentration: 0.5 mg/ml -

Descripción

Neurobeachin (NBEA) is a multi-domain protein involved in the regulation of synaptic function, neuronal signaling, and cell adhesion NBEA is particularly abundant in the brain, where it plays a role in neuronal growth, synaptic plasticity, and the maintenance of neuronal structure It interacts with a variety of proteins involved in synaptic signaling and vesicle trafficking, contributing to the organization of the postsynaptic density and the regulation of neurotransmitter receptor trafficking NBEA is essential for the proper function of neurons, particularly in areas involved in learning and memory, and its dysfunction is linked to neurological disorders such as neurodevelopmental disorders and intellectual disability Mutations in NBEA disrupt neuronal connectivity and signaling, leading to impaired cognitive function Understanding NBEA’s role in neuronal health could provide insights into therapies for treating neurodevelopmental and neurodegenerative diseases

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