Neurobeachin (NBEA) Antibody

416€ (200 µl)
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935106861
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name
Neurobeachin (NBEA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431838
tested applications
P-ELISA, IHC
Description
Neurobeachin Antibody is a Goat Polyclonal antibody against Neurobeachin.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Neurobeachin (NBEA) |
Host | Goat |
Reactivity | Human |
Recommended Dilution | P-ELISA: 1/4000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Size 1 | 200 µl |
Form | Liquid |
Tested Applications | P-ELISA, IHC |
Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 26960, 26422 |
NCBI Accession | NP_056493.3, NP_001191126.1 |
Alias | BCL8B,LYST2,NEDEGE,Protein BCL8B,Lysosomal-trafficking regulator 2 |
Background | Antibody anti-NBEA |
Status | RUO |
Note | Concentration: 0.5 mg/ml - |
Descripción
Neurobeachin (NBEA) is a multi-domain protein involved in the regulation of synaptic function, neuronal signaling, and cell adhesion NBEA is particularly abundant in the brain, where it plays a role in neuronal growth, synaptic plasticity, and the maintenance of neuronal structure It interacts with a variety of proteins involved in synaptic signaling and vesicle trafficking, contributing to the organization of the postsynaptic density and the regulation of neurotransmitter receptor trafficking NBEA is essential for the proper function of neurons, particularly in areas involved in learning and memory, and its dysfunction is linked to neurological disorders such as neurodevelopmental disorders and intellectual disability Mutations in NBEA disrupt neuronal connectivity and signaling, leading to impaired cognitive function Understanding NBEA’s role in neuronal health could provide insights into therapies for treating neurodevelopmental and neurodegenerative diseases
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