Neural Cell Adhesion Molecule L1 (L1CAM) Antibody
195€ (20 µl)
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Name
Neural Cell Adhesion Molecule L1 (L1CAM) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx124193
Tested Applications
ELISA, WB, IF/ICC
Description
L1CAM Antibody is a Rabbit Polyclonal Antibody against L1CAM.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Neural Cell Adhesion Molecule L1 (L1CAM) Immunogen: Recombinant protein corresponding to L1CAM. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2.056 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 140 kDa Observed MW: 85/200-250 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32004 |
| Gene ID | 3897 |
| NCBI Accession | NP_000416.1 |
| Alias | S10,HSAS,HYCX,MASA,MIC5,SPG1,CAML1,CD171,HSAS1,N-CAML1,NCAM-L1,N-CAM-L1,Neural cell adhesion molecule L1 |
| Background | Antibody anti-L1CAM |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
L1 Cell Adhesion Molecule (L1CAM) is a critical protein in the nervous system that belongs to the immunoglobulin superfamily. It plays a significant role in neural development, influencing processes such as axonal guidance, neuronal migration, and synaptic plasticity. L1CAM is predominantly expressed in the brain but is also found in other tissues, contributing to various cellular interactions. It is a transmembrane glycoprotein that mediates homophilic (L1-L1) and heterophilic (L1 with other molecules) binding, facilitating cell-cell adhesion and communication. Research into L1CAM has provided insights into its importance in both normal neural development and pathological conditions.
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