Neural Cell Adhesion Molecule L1 (L1CAM) Antibody

Este producto es parte de L1CAM - L1 cell adhesion molecule
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195€ (20 µl)

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935106861
info@markelab.com
name
Neural Cell Adhesion Molecule L1 (L1CAM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx124193
tested applications
ELISA, WB, IF/ICC

Description

L1CAM Antibody is a Rabbit Polyclonal Antibody against L1CAM.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Neural Cell Adhesion Molecule L1 (L1CAM)
Immunogen: Recombinant protein corresponding to L1CAM. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 2.056 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 140 kDa  Observed MW: 85/200-250 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P32004
Gene ID
3897
NCBI Accession
NP_000416.1
Alias
S10,HSAS,HYCX,MASA,MIC5,SPG1,CAML1,CD171,HSAS1,N-CAML1,NCAM-L1,N-CAM-L1,Neural cell adhesion molecule L1
Background
Antibody anti-L1CAM
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

L1 Cell Adhesion Molecule (L1CAM) is a critical protein in the nervous system that belongs to the immunoglobulin superfamily. It plays a significant role in neural development, influencing processes such as axonal guidance, neuronal migration, and synaptic plasticity. L1CAM is predominantly expressed in the brain but is also found in other tissues, contributing to various cellular interactions. It is a transmembrane glycoprotein that mediates homophilic (L1-L1) and heterophilic (L1 with other molecules) binding, facilitating cell-cell adhesion and communication. Research into L1CAM has provided insights into its importance in both normal neural development and pathological conditions.

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