Natural Killer Cells Antigen CD94 (KLRD1) Antibody (FITC)
364€ (100 tests)
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Name
Natural Killer Cells Antigen CD94 (KLRD1) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139675
Tested Applications
FCM
Description
CD94 Antibody is a Mouse Monoclonal against CD94.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Natural Killer Cells Antigen CD94 (KLRD1) Immunogen: Cultured Human NK cells. |
| Host | Mouse |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | FCM: 4 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user.The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 Kappa |
| Clone ID | S339 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q13241 |
| Gene ID | 3824 |
| Alias | Natural killer cells antigen CD94,CD94,KP43,Killer cell lectin-like receptor subfamily D member 1,NK cell receptor |
| Background | Antibody anti-KLRD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Killer Cell Lectin-Like Receptor D1 (KLRD1), commonly known as CD94, is a transmembrane protein that plays a crucial role in the immune system. Expressed on the surface of natural killer (NK) cells and certain subsets of T-cells, KLRD1 is primarily involved in recognizing and responding to infected or transformed cells. KLRD1 is part of the C-type lectin-like family of receptors, and its main function is to pair with other receptors (e.g., NKG2 family members) to mediate immune surveillance by recognizing peptide-loaded MHC class I molecules. Unlike other immune receptors that directly recognize pathogenic antigens, KLRD1 primarily regulates immune response through interaction with HLA-E, a non-classical MHC class I molecule presenting peptide sequences derived from other MHC class I molecules.
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