Natural Killer Cells Antigen CD94 (KLRD1) Antibody
286€ (50 tests)
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Name
Natural Killer Cells Antigen CD94 (KLRD1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx270074
Tested Applications
FCM
Description
Killer Cell Lectin Like Receptor Subfamily D, Member 1 (KLRD1) Antibody is a Rabbit Polyclonal Antibody against Killer Cell Lectin Like Receptor Subfamily D, Member 1 (KLRD1) for use in flow cytometry.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Natural Killer Cells Antigen CD94 (KLRD1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 50 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Size 4 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Natural killer cells antigen CD94,CD94,KP43,Killer cell lectin-like receptor subfamily D member 1,NK cell receptor |
| Background | Antibody anti-KLRD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Killer Cell Lectin-Like Receptor D1 (KLRD1), commonly known as CD94, is a transmembrane protein that plays a crucial role in the immune system. Expressed on the surface of natural killer (NK) cells and certain subsets of T-cells, KLRD1 is primarily involved in recognizing and responding to infected or transformed cells. KLRD1 is part of the C-type lectin-like family of receptors, and its main function is to pair with other receptors (e.g., NKG2 family members) to mediate immune surveillance by recognizing peptide-loaded MHC class I molecules. Unlike other immune receptors that directly recognize pathogenic antigens, KLRD1 primarily regulates immune response through interaction with HLA-E, a non-classical MHC class I molecule presenting peptide sequences derived from other MHC class I molecules.
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